منابع مشابه
Ammonium effects on colonic Cl- secretion: anomalous mole fraction behavior.
A significant amount of ammonium (NH4+) is absorbed by the colon. The nature of NH4+ effects on transport and NH4+ transport itself in colonic epithelium is poorly understood. The goal of this study was to elucidate the effects of NH4+ on cAMP-stimulated Cl- secretion in the colonic cell line T84. In HEPES-buffered solutions, application of basolateral NH4+ resulted in a reduced level of Cl- se...
متن کاملThe anomalous mole fraction effect in calcium channels: a measure of preferential selectivity.
The cause of the anomalous mole fraction effect (AMFE) in calcium-selective ion channels is studied. An AMFE occurs when the conductance through a channel is lower in a mixture of salts than in the pure salts at the same concentration. The textbook interpretation of the AMFE is that multiple ions move through the pore in coordinated, single-file motion. Instead of this, we find that at its most...
متن کاملThree Years of Sciamachy Carbon Dioxide and Methane Column-averaged Dry Air Mole Fraction Measurements
Carbon dioxide (CO2) and methane (CH4) are the two most important anthropogenic greenhouse gases. The near-infrared nadir spectra of reflected solar radiation measured by SCIAMACHY on-board ENVISAT contain information on the vertical columns of these gases which we retrieve using a new version of the scientific algorithm WFM-DOAS (version 1.0). Our main data products are column-averaged dry air...
متن کاملIonic Coulomb blockade and anomalous mole fraction effect in NaChBac bacterial ion channels
We report an experimental study of the influences of the fixed charge and bulk ionic concentrations on the conduction of biological ion channels, and we consider the results within the framework of the ionic Coulomb blockade model of permeation and selectivity. Voltage clamp recordings were used to investigate the Na/Ca anomalous mole fraction effect (AMFE) exhibited by the bacterial sodium cha...
متن کاملReinterpreting the anomalous mole fraction effect: the ryanodine receptor case study.
The origin of the anomalous mole fraction effect (AMFE) in calcium channels is explored with a model of the ryanodine receptor. This model predicted and experiments verified new AMFEs in the cardiac isoform. In mole fraction experiments, conductance is measured in mixtures of ion species X and Y as their relative amounts (mole fractions) vary. This curve can have a minimum (an AMFE). The tradit...
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ژورنال
عنوان ژورنال: Journal of Chemical Education
سال: 1968
ISSN: 0021-9584,1938-1328
DOI: 10.1021/ed045p622.2